Prof   AWH Neitz

Office:  3-34 Agriculture Building

Tel: 12-420-2906

Fax: 12-362-5302

E-mail: albert.neitz [at] bioagric.up.ac.za

Principal Investigator: Tick Research Group

 

Recent Publications

• BIRKHOLTZ, L-M, JOUBERT, F, NEITZ, AWH & LOUW, AI (2003). Comparative properties of a three-dimensional model of Plasmodium falciparum ornithine decarboxylase. Proteins: Structure, Function and Genetics, 50, 464-473.
• EHEBAUER, MT, MANS, BJ, GASPAR, ARM & NEITZ, AWH. (2002). Identification of extrinsic blood coagulation pathway inhibitors from the tick Ornithodoros savignyi (Acari: Argasidae). Experimental Parasitology, 101, 138-148.
• JOUBERT, F., NEITZ, A.W.H. & LOUW, A.I. (2001). Structure-based inhibitor screening: A family of sulfonated dye inhibitors for malaria parasite triosephosphate isomerase. Proteins: Structure, Function, and Genetics, 45, 136-143.
• MANS, B.J., COETZEE, J., LOUW, A.I., GASPAR, A.R.M. & NEITZ, A.W.H. (2000). Disaggregation of aggregated platelets by apyrase from the tick, Ornithodoros savignyi (Acari: Argasidae). Experimental & Applied Acarology, 24, 271-282.
• MANS, B.J., LOUW, A.I. & NEITZ, A.W.H. (2002). Amino acid sequence and structure modeling of savignin, a thrombin inhibitor from the tick, Ornithodoros savignyi. Insect Biochemistry and Molecular Biology, 32, 821-828.
• MANS, B.J., LOUW, A.I. & NEITZ, A.W.H. (2002). Disaggregation of aggregated platelets by savignygrin, a a_IIbb₃ antagonist from Ornithodoros savignyi. Experimental and Applied Acarology, 27, 231-239.
• MANS, B.J., LOUW, A.I. & NEITZ, A.W.H. (2002). Evolution of hematophagy in ticks: common origins for blood coagulation and platelet aggregation inhibitors from soft ticks of the genus Ornithodoros. Molecular Biology and Evolution, 19(10), 1695-1705.
• MANS, B.J., LOUW, A.I. & NEITZ, A.W.H. (2002). Savignygrin, a platelet aggregation inhibitor from the soft tick, Ornithodoros savignyi, presents the RGD integrin recognition motif on the Kunitz-BPTI fold. The Journal of Biological Chemistry, 277(24), 21371-21378.
• MANS, B.J., STEINMANN, C.M.L., VENTER, J.D., LOUW, A.I. & NEITZ, A.W.H. (2002). Pathogenic mechanisms of sand tampan toxicoses induced by the tick, Ornithodoros savignyi. Toxicon 40, 1007-1016.
• MANS, B.J., VENTER, J.D., VREY, P.J., LOUW, A.I. & NEITZ, A.W.H. (2001). Identification of putative proteins involved in granule biogenesis of tick salivary glands. Electrophoresis 22, 1739-1746.
• MARITZ, C., LOUW, A.I., GOTHE, R. & NEITZ, A.W.H. (2000). Detection and micro-scale isolation of a low molecular mass paralysis toxin from the tick Argas (Persicargas) walkerae. Experimental & Applied Acarology, 24, 615-630.
• MARITZ, C., LOUW, A.I., GOTHE, R. & NEITZ, A.W.H. (2001). Neuropathogenic properties of Argas (persicargas) walkerae larval homogenates. Comparative Biochemistry and Physiology, Part A, 128(2), 233-239.